Responses API.
Use the other APIs when you need embeddings, audio, moderation, image generation, or when you need to keep an existing client format.
Comparison
Quick choices
- New text, multimodal, tool, or agent flows: use Responses API.
- Retrieval, ranking, or semantic search: use Embeddings API.
- TTS, transcription, or translation: use Audio API.
- Text or image safety checks: use Moderations API.
- Direct image generation or image editing: use Images API.
- Existing OpenAI
messages[]integration: use Chat Completions API. - Existing Anthropic-style integration: use Messages API.
Decision Shortcuts
Responses API
Start here for new LLM apps and most feature-complete integrations.
Embeddings API
Use this for vector generation and retrieval pipelines.
Audio API
Use this for speech synthesis, transcription, and translation.
Moderations API
Use this for safety checks over text and images.
Compatibility Layers
Use a compatibility API only when keeping the existing client format matters more than starting from the cleanest default.- Chat Completions API keeps the OpenAI chat request format.
- Messages API keeps the Anthropic Messages request format.
Responses API is usually the simpler choice.